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The Genetic Iron Curtain: Differences between East and West in Polygenic Scores

Two polygenic scores reveal a striking East-West contrast - but the geography looks more like overlapping gradients than a biological wall.

Davide Piffer's avatar
Davide Piffer
Sep 12, 2026
∙ Paid

Europe’s less familiar genetic axis

When people talk about genetic differences within Europe, they usually reach first for the north-south axis. The familiar stereotypes come with it: tall, blonde northerners contrasted with medium-height, dark-haired southerners. These images are crude, but they reflect how readily Europeans imagine biological variation from Scandinavia to the Mediterranean.

East and West are usually discussed in a different vocabulary. Here the reference points are political systems, religion, conservatism, family structure, the historical Iron Curtain, or the Hajnal line separating long-standing European marriage patterns. Genetic differences across the same axis receive much less attention.

This post sheds some light on that neglected comparison. I examine two polygenic scores (PGSs): EA4, built from variants associated with educational attainment, and a score built from variants associated with adult height. I compare Eastern and Western Europeans, then ask whether the scores vary with longitude, latitude, or both. The result is an East-West contrast, but not a simple genetic border.

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